Cart
sales@molnova.com
MJ 15
CAS No. 944154-76-1
MJ 15( —— )
Catalog No. M33886 CAS No. 944154-76-1
MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 47 | Get Quote |
|
| 5MG | 107 | Get Quote |
|
| 10MG | 167 | Get Quote |
|
| 25MG | 342 | Get Quote |
|
| 50MG | 548 | Get Quote |
|
| 100MG | 863 | Get Quote |
|
| 500MG | 1728 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMJ 15
-
NoteResearch use only, not for human use.
-
Brief DescriptionMJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.
-
DescriptionMJ15 is a potent and selective CB1 receptor antagonist with a Ki of 27.2 pM and an IC50 of 118.9 pM for rat CB1 receptors. MJ15 exhibits potency in obesity and hyperlipidemia models. MJ15 inhibits food intake and increases in body weight in diet-induced obese rats and mice.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetCannabinoid Receptor
-
RecptorCannabinoid Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number944154-76-1
-
Formula Weight471.77
-
Molecular FormulaC23H17Cl3N4O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NCC=1C=NC=CC1)C2=NN(C3=CC=C(Cl)C=C3Cl)C(C=4C=CC(Cl)=CC4)=C2C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chen W, et al. Novel selective antagonist of the cannabinoid CB1 receptor, MJ15, with prominent anti-obesity effect in rodent models. Eur J Pharmacol. 2010 Jul 10;637(1-3):178-85. ?
molnova catalog
related products
-
LY2828360
LY2828360 is a cannabinoid (CB) receptor 2 agonist (Ki = 40.3 nM). It selectively activates CB2 over CB1 in a GTPγS binding assay (EC50s = 20.1 and >100000 nM respectively).
-
Org 27569
Org 27569 is a potent, selective, allosteric modulator of cannabinoid CB1 receptor.
-
AM-1221
A potent and selective agonist for the cannabinoid receptor CB1 with Ki of 0.28 nM, 180-fold selectivity over CB2.
